Which of the following neoplasms is the most likely cause of polyuria in this patient?

A 14-year-old boy presents with 3 months of lethargy, headaches, and muscle weakness. His parents note that he drinks water excessively. His vital signs are normal. A 24-hour urine collection shows polyuria. The fasting blood sugar is normal. An X-ray film of the brain reveals suprasellar calcification. An autopsy specimen of a similar case is shown in the image. Which of the following neoplasms is the most likely cause of polyuria in this patient?

image

  1. Craniopharyngioma
  2. Glioblastoma multiforme
  3. Pheochromocytoma
  4. Pituitary adenoma
  5. Retinoblastoma