Which is incorrect about Buerger’s disease?
1.Ischemia of nerves
2.Deep vein thrombosis
Ref: Robbing pathology 9th ed. 1512-15; Robbins 8th ed. / 517
• Buerger disease is associated with HLA B-5 and HLA-A9.
• In thrombongitis obliterans there is acute and chronic segmental inflammation of vessels with thrombosis in the lumen
• Typically, the thrombus contains microabscesses with a central focus of neutrophils surrounded by inflammation
• Later, the inflammatory process extends into contiguous veins and nerves and in time all the (arteries, veins and nerves) become encased in fibrous tissue, a characteristic that is very rare with vasculitis.