Question 1: With reference to infections with Escherichia coli the
following are true except ?
A) Enteroaggregative E.coli is associated with Persistent diarrhoea
B) Enterohemorrhagic E.coli can cause haemolytic uraemic syndrome
C) Enteroinvasive E.coli produces a disease similar to salmonellosis
D) Enterotoxigenic E.coli is a common cause of traveler’s diarrhoea
Answer: C) Enteroinvasive E.coli produces a disease similar to
salmonellosis
Question 2: The following statements are true regarding melioidosis
except ?
A) It is caused by Burkholderia mallei
B) The agent is a gram negative aerobic bacteria
C) Bipolar staining of the aetiological agent is seen with methylene blue
stain
D) The most common form of melioidosis is pulmonary infection
Answer: A) It is caused by Burkholderia mallei
Question 3: All of the following Vibrio sp. are halophilic, except ?
A) V.cholerae
B) V.parahaemolyticus
C) V.alginolyticus
D) V.fluvialis
Answer: A) V.cholerae
Question 4: All of the following organisms are known to survive
intracellularly except ?
A) Neisseria meningitides
B) Salmonella typhi
C) Streptococcus pyogenes
D) Legionella pneumophila
Answer: C) Streptococcus pyogenes
Question 5: The capsule of Cryptococcus neoformans in a CSF sample is
best seen by ?
A) Grams stain
B) India ink preparation
C) Giemsa stain
D) Methanamine - Silver stain
Answer: B) India ink preparation
Question 6: Viruses can be isolated from clinical samples by cultivation
in the following except ?
A) Tissue culture
B) Embryonated eggs
C) Animals
D) Chemically defined media
Answer: D) Chemically defined media
Question 7: It is true regading the normal microbial flora present on the
skin and mucous membranes that ?
A) It cannot be eradicated by antimicrobial agents
B) It is absent in the stomach due to the acidic pH
C) It establishes in the body only after the neonatal period
D) The flora in the small bronchi is similar to that of the trachea
Answer: A) It cannot be eradicated by antimicrobial agents
Question 8: An army jawan posted in a remote forest area had fever and
headache. His fever was 104°F and pulse was 70 per min. He had an
erythematous lesion of about 1 cm on the leg surrounded by small vesicles,
along with generalized lymphadenopathy at the time of presentation to the
referral hospital. His blood sample was collected to perform serology for
the diagnosis of Rickettsial disease. Which one of the following results in
Weil-felix reaction will be diagnostic in this clinical setting ?
A) High OX-2
B) High OX-19
C) High OX-K
D) High OX-19 and OX-2
Answer: C) High OX-K
Question 9: Adenosine deaminase (enzyme) deficiency is associated with ?
A) Severe combined immunodeficiency (SCID)
B) X-linked agammaglobulinemia
C) Transient hypogammaglobulinemia of infancy
D) Chronic granulomatous disease
Answer: A) Severe combined immunodeficiency (SCID)
Question 117: The serum concentration of which of the following human IgG
subclass is maximum ?
A) IgG1
B) IgG2
C) IgG3
D) IgG4
Answer: A) IgG1
Question 10: Chlamydia trachomatis is associated with the following except
?
A) Endemic trachoma
B) Inclusion conjunctivitis
C) Lymphogranuloma venereum
D) Community acquired pneumonia
Answer: D) Community acquired pneumonia
Question 11: The following statements are true regarding Clostridium
perfringens except ?
A) It is the commonest cause of gas gangrene
B) It is normally present in human faeces
C) The principal toxin of C.perfringens is the alpha toxin
D) Gas gangrene producing strains of C.perfringens produce heat resistant
spores
Answer: D) Gas gangrene producing strains of C.perfringens produce heat
resistant spores
Question 12: A child was diagnosed to be suffering from diarrhoea due to
Camplyobacter jejuni. Which of the following will be the correct
enviornmental conditions of incubation of the culture plates of the stool
sample ?
A) Temperature of 42°C and microaerophilic
B) Temperature of 42°C and 10% carbondioxide
C) Temperature of 37°C and microaerophilic
D) Temperature of 37°C and 10% carbondioxide
Answer: A) Temperature of 42°C and microaerophilic
Question 13: Which one of the following statements is true regarding
Chlamydia pneumoniae ?
A) Fifteen serovars have been identified as human pathogens
B) Mode of transmission is by the airborne bird excreta
C) The cytoplasmic inclusions present in the sputum specimen are rich in
glycogen
D) The group specific antigen is responsible for the production of
complement fixing antibodies
Answer: D) The group specific antigen is responsible for the production of
complement fixing antibodies
Question 14: Virus mediated transfer of host DNA from one cell to another
is known as ?
A) Transduction
B) Transformation
C) Transcription
D) Integration
Answer: A) Transduction
Question 15: HIV can be detected and confirmed by ?
A) Polymerase Chain Reaction (PCR)
B) Reverse Transcriptase - PCR
C) Real Time PCR
D) Mimic PCR
Answer: B) Reverse Transcriptase - PCR
Question 16: In the small intestine, cholera toxin acts by ?
A) ADP-ribosylation of the G regulatory protein
B) Inhibition of adenyl cyclase
C) Activation of GTPase
D) Active absorption of NaCl
Answer: A) ADP-ribosylation of the G regulatory protein