Q 89. A highly ionized drug:
A. Is excreted mainly by the kidney.
B. Can cross the placental barrier easily.
C. Is well absorbed from the intestine.
D. Accumulates in the cellular lipids
Q 90. Which one of the following drugs is ‘topoisomerase 1 inhibitor’?
Q 91. The following drugs have significant drug interaction with digoxin,
B. Thiazide diuretics.
Q 92. One of the following is not true about nesiritide:
A. It is a brain natriuretic peptide analogue.
B. It is used in acutely decompensated heart failure.
C. It has significant oral absorption.
D. It has a short half-life.
Q 93. Antipsychotic drug-induced parkinsonism is treated by:
Q 94. Which one of the following is used in therapy of toxoplasmosis?
Q 95. The following statements regarding finasteride are true except:
A. It is used in the medical treatment of benign prostatic hypertrophy (BPH)
B. Impotence is well documented after its use.
C. It blocks the conversion of dihydrotestosterone to testosterone.
D. It is a 5-a reductase inhibitor.
Q 96. Eternacept acts by one of the following mechanisms:
A. By blocking tumor necorosis factor.
B. By blocking bradykinin synthesis.
C. By inhibiting cyclo-oxygenase-2.
D. By blocking lipoxygenase.
Q 97. In unconjugated hyperbilirubinemia, the risk of kernicterus increases with
the use of:
Q 98. All of the following are topically used sulphonamides except:
C. Silver sulphadiazine.
Q 99. Oculogyric crisis is know to be produced by all of the following drugs
Q 100. Which of the following drugs is useful in prophylaxis of migraine?
Q 101. Inverse agonist of benzodiazepine receptor is:
Q 102. The group of antibiotics which possess additional anti-inflammatory and
immunomodulatory activities is:
B. Polypeptide antibiotics.
Q 103. With which of the following theophylline has an antagonistic interaction?
A. Histamine receptors.
B. Bradykinin receptors.
C. Adenosine receptors.
D. Imidazoline receptors.
Q 104. One of the following is not penicillinase susceptible:
B. Penicillin G.
Q 105. Which one of the following is best associated with lumefantrine?
Q 106. Which one of the following drugs increases gastro-intestinal motility?
Q 107. Nevirapine is a:
A. Protease inhibitor.
B. Nucleoside reverse transcriptase inhibitor.
C. Non-nucleoside reverse transcriptase inhibitor.
D. Fusion inhibitor.