Osteoporosis is given a diuretic to treat her hypertension

A 67-year-old woman with osteoporosis is given a diuretic to treat her hypertension. This particular diuretic has the adverse effect of limiting calcium excretion by the kidney. Referring to the image, where along the nephron does this drug act?

image

  1. A
  2. B
  3. C
  4. D
  5. E

View Explanation

The only diuretics that specifically limit calcium loss are the thiazides. They act in the early distal tubule, which is marked as region E in the image.