Contre—coup injuries are seen in :
1. Diazepam
2. Brain
3. Ethyl alcohol
4. Flumazenil
A segment of a eukaryotic gene that is not represented in the mature messenger RNA is known as:
1. Exon
2. TATA box
3. Intron
4. Plasmid
Commonest cause of cannon waves is:
1. None of the above
2. Complete heart block
3. Junctional rhythm
4. Ventricular ectopic beats
Shine Dalgarno sequence in bacterial mRNA is near:
1. UGA codon
2. AUG codon
3. UAG codon
4. UAA codon
Which of the following drug is most commonly used world wide in maintenance doses for opioid dependence
1. Methadone
2. Naltrexone
3. lmipramine
4. Disulfiram
A 30 year old pregnant woman developes tuberculosis. Which of the following antitubercular drugs should not be used:
1. INH
2. Ethambutol
3. Rifampicin
4. Streptomycin
Toxins are implicated as the major pathogenetic mechanism in all of the following bacterial diarrhoeas except?
1. Vibrio cholerae
2. Staphylococcus aureus
3. Shigella sp.
4. Vibrio parahaemolyticus
Alpha helix and Beta pleated sheet are examples of:
1. Primary structure
2. Secondary structure
3. Tertiary structure
4. Quaternary structure
Which of the following gene defect is associated with development of medullary carcinoma of thyroid?
1. RET protooncogene
2. Rb gene
3. BRCA 1 gene
4. FAP gene
A small calcium binding protein that modifies the activity of many enzymes and other proteins in response to changes of Ca2+ concentration, is known as:
1. Cycline
2. Calmodulin
3. Collagen
4. Kinesin
False about pneumococcus is?
1. Commonest cause of otitis media and pneumonia
2. Capsule aids in virulence
3. Meningitis caused by it is milder than by other organisms
4. Bile sensitive
Methotrexate is used in all except:
1. Psoriasis
2. Sickle cell anemia
3. Rheumatoid arthritis
4. Ankylosing spondylitis
Which of the following is not part of Beck’s compression triad:
1. Hypotension
2. Muffled heart sounds
3. Elevated JVP
4. Pulsus paradoxus
Epstein Barr (EB) virus has been implicated in the following malignancies except:
1. Hodgkin‘s disease
2. Non Hodgkin‘s lymphoma
3. Nasopharyngeal carcinoma
4. Multiple myeloma
Which of the following is not a cause of high output cardiac failure?
1. Thyrotoxicosis
2. Beriberi
3. Dilated cardiomyopathy
4. Anemia
Summation gallop is the fusion of:
1. S1 and S2
2. S4 and S1
3. S2 and S3
4. S3 and S4
Which is not an autoimmune disease?
1. SLE
2. Grave’s disease
3. Myasthenia gravis
4. Sickle cell disease
Dietary changes advocated by WHO for prevention of heart diseases include all of the following except?
1. Consumption of saturated fats be limited to less than 10% of total energy intake
2. A decrease in complex carbohydrate consumption
3. Reduction in fat intake to 20-30 percent of caloric intake
4. Reduction of cholesterol to below l00mg per kcal per day
Dietary changes advocated by WHO for prevention of heart diseases include all of the following except?
1. Consumption of saturated fats be limited to less than 10% of total energy intake
2. A decrease in complex carbohydrate consumption
3. Reduction in fat intake to 20-30 percent of caloric intake
4. Reduction of cholesterol to below l00mg per kcal per day
Which of the following is a high risk non cardiac surgery with respect to cardiac risk?
1. Trans urethral resection of prostate
2. Hip replacement
3. Femoro-popliteal bypass
4. Radical mastectomy
All of the following are associated with low complement levels except:
1. Mesangio capillary glomerulonepltritis
2. Lupus nephritis
3. Post—infections glomerulonephritis
4. Diarrhea-associated hemolytic uremic syndrome
Which of the following antihypertensive drugs should not be used in a patient on Lithium in order to prevent Lithium Toxicity?
1. Clonidine
2. Calcium Channel Blockers
3. Beta blockers
4. Diuretics
A 37 weeks pregnant woman attends an antenatal clinic at a Primary Health Centre. She has not had any antenatal visit till now. The best approach regarding tetanus immunization in this case would be to
1. Do not waste the TT vaccine as it would anyhow be of no use in this pregnancy
2. Give her anti-tetanus Immunoglobulin along with the TT vaccine
3. Give a dose of Tetanus Toxoid (TT) and explain to her that it will not protect the new born and she should take the second dose after four weeks even if she delivers in the meantime
4. Give one dose of TT and explain that it will not be useful for this pregnancy
All of the following statements regarding Corynebacterium diphtheriae are true, except?
1. It can be identified by using tests for toxigenicity
2. The toxin inhibits protein synthesis
3. Toxin has adverse effects on cardiovascular and nervous systems
4. Native chromosome is responsible for toxin production
Which of the following does not bind to GABA receptor chloride channels?
1. Buspirone
2. Ethanol
3. Alfaxalone
4. Zolpidem
Amiodarone, a class III anti arrhythmic agent, was initially developed as an:
1. Anti anginal agent
2. Anti arrhythmic agent
3. None of the above
4. Anti coagulant