Regarding myasthenia..all are true except
A.initially involve eye and pharynx
B.temporarily improve by neostigmine
C.causes thymic hyperplasia
D.Symptoms can relieve by rest
E.increase amplitude of end plate potentials
•severe hypertension (e.g. >200/130 mmHg)
•occurs in both essential and secondary types
•fibrinoid necrosis of blood vessels, leading to retinal haemorrhages, exudates, and proteinuria, haematuria due to renal damage (benign nephrosclerosis).
•can lead to cerebral oedema –> encephalopathy
•classically: severe headaches, nausea/vomiting, visual disturbance
•however chest pain and dyspnoea common presenting symptoms
•severe: encephalopathy (e.g. seizures)
•reduce diastolic no lower than 100mmHg within 12-24 hrs
•most patients: oral therapy e.g. atenolol
•if severe/encephalopathic: IV sodium nitroprusside/labetolol
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