Ampicillin and amoxicillin are in the same group of penicillins. Which of the following statements best characterizes amoxicillin?
1.It has better oral absorption than dose ampicillin
2.It can be used in penicillinase-producing organisms
3.It is classified as a broad-spectum penicillin
4.It does not cause hypersensitivity reactions
5.It is effective against pseudomonas
Explanation
Amoxicillin is classified as an aminopenicillin along with ampicillin. Because it is less affected than ampicillin by the presence of food, it has a superior absorption in the GI tract. It is sensitive to penicillinase and has a narrow spectrum of activity toward certain Gram-positive and Gram-negative organisms, but not Pseudomonas. Because it is in the penicillin family, hypersensitivity reactions are a possibility