Q-4. Drug that can be used for producing alkalinization of urine is? (NEET Based)
a) Hydro-chlorthiazide
b) Furosemide
c) Acetazolamide
d) Spironolactone
Answer: Acetazolamide
Explanation:
Clinical uses of Acetazolamide:
Glaucoma
To alkalinize urine for urinary tract infection or to promote excretion of certain acidic drugs
Epilepsy
Acute mountain sickness
Periodic paralysis
Important point:
Raised level of CO2 in brain and lowering of pH-> raising seizure threshold