Q-1. Which of the following is the muscle relaxant of choice in renal failure?
a) Rapacurium
b) Pancuronium
c) Atracurium
d) Rocuronium
Answer: Atracurium
Explanation:
Atracurium is a new, non-depolarizing muscle relaxant which rapidly breaks down in vivo and appears to require neither renal nor hepatic function for its elimination.
It is spontaneously broken down in the plasma by a non-enzymatic chemical process “Hofmann’s degradation”. Thus it is non-cumulative.
It could be used in patients with either liver or kidney disease.
It is the relaxant of choice in fragile patients and in renal failure.