Which anaesthetic agent is preferred in a patient taken for surgery with bilirubin of 8.6 mg/dl and serum creatinine of
2.1 mg/dl ?
A. Atracurium
B. Vecuronium
C. Pancuronium
D. Rocuronium
Correct answer : A. Atracurium
Atracurium is the preferred muscle relaxant in a patient withliver dysfunction / renal failure
It undergoes non specific ester hydrolysis and nonenzymatic degradation ( Hoffman degradation )
It does not depend on the liver / kidney for its deactivationOther muscle relaxants that can be given in liver / renal
disease are Cisatracurium and Mivacurium