AIIMS November 2011 – MCQ 108

Chymotrypsinogen is a
A. Zymogen
B. Carboxypeptidase
C. Transaminase
D. Elastase

(Repeat question – AIIMS Nov 06 – AA q22)

Correct answer: A. Zymogen

A zymogen (or proenzyme) is an inactive enzyme precursor. A zymogen requires a biochemical change (such as a hydrolysis reaction revealing the active site, or changing the configuration to reveal the active site) for it to become an active enzyme.