A 47-year-old woman presents to the physician with weight gain, fatigue, and lethargy. She says her appetite has decreased recently, and she has been constipated. A thyroid biopsy shows an enlarged, symmetric, and fi rm thyroid. Histological findings are signifi cant for a lymphocytic and plasma cell infiltrate with occasional germinal center formation. Follicles contain little colloid, while the follicular epithelial lining shows enlarged epithelial cells containing acidophilic cytoplasm. Results of laboratory tests are pending. Which of the following antibodies would most likely be found in this patient?
(A) Anti-basement membrane antibodies
(B) Anti-epithelial cell antibodies
© Antimicrosomal antibodies
(D) Antimitochondrial antibodies
(E) Antineutrophil antibodies