1) Proteoglycans in Basement Membrane : Heparan sulfate
2) Smoker (Image Squamous to Columnar change): Metaplasia
3) Werner cause - DNA helicase mutation
4) NO is synthesised from- Arginine
5) Granuloma with horseshoe type nuclei containing giant cells in a case with cough and lymphadenopathy and history of cough : TB
6) Pedigree chart with history of Marfan syndrome – AD
7) True about Huntington - Trinucleotide disorder
8 ) Superantigen is produced by which of the following : Streptococcus
9) Interleukin for production of IgE Ab: IL4
10) Isograft - between twins
11) Post-transplant mc infection:CMV
12) SlE like rash.
13) Wiskott Aldrich syndrome
14) Initiator of thrombosis: - Endothelial injury
15) Young male post fracture of tibia having paco2 as 60%. What is the diagnosis : FAT EMBOLISM
16) Patient on warfarin therapy, clotting factor affected via Gamma carboxylation step: Factor 2 (Vit K dep)
17) CPD is better than ACD: - Decreases acidity /improves oxygen transport
18) ileal resection: Vitamin b12 def
19) Vitamin B12 rich: Animal food
20) A 25 year old male with fatigue, Hb 9gm%, MCV 102 fl, Peripheral smear with Macrocytic RBC and hyper segmented neutrophils: Megaloblastic Anemia
21) 10 years old child with abdominal pain, painful extremities with anaemia, and shrunken spleen (auto splenectomy): Sickle cell Anaemia
22) Trans retinoic acid used in treatment of tumour related to :- PML RARA (Acute Promyelocytic Leukemia)
23) Non smoker with lung gross (Emphysema) - Alpha 1 antitrypsin
24) PAN - HBsAg positive.
25) Kawasaki disease: Conjunctivitis, cervical ln, polymorphic rash.
26) Recurrent oral ulcer with venous thrombosis-BECHETS Disease
27) Reperfusion injury (Histopathology change in reperfusion injury) :- contraction bands necrosis
28) Endocarditis: Large ,friable vegetations seen in? Bulky vegetations - Infective vegetations
29) Loss of foot process – MCD
30) Patient with malaise, hematuria. HPE showing crescentric GN. EM with arrow pointing at breaks in GBM (RPGN) with no history of hemoptysis. Next step – anti-GBM
31) ADPKD patient with c/o loose stool and abdominal pain : Colonic diverticulosis
32) bowel loops right to umbilicus condition associated is-gastrochisis
33) Person ate last night heavily. Morning pain abdomen. X-ray, pneumomediastinum, Spontaneous rupture of Esophagus (Boerhaav syndrome )
34) Hirschsprung’s disease due to-failure of migration of neural crest cells
35) In achalasia which is reduced- NO and VIP is REDUCED.
36) Celiac - diarrhoea with villous atrophy and CD8 Lymphocytic infiltrates: Antigliadin antibodies.
37) A 5 years child with rectal polyp HPE - Juvenile polyp
38) Recurrent episodes of pain, abdomen tenderness, fever and jaundice -Primary sclerosing Cholangitis
39) A 42 year old patient with obstructive jaundice, ALP, GGT and haptoglobin is increased- Alcoholic liver disease
40) In Multiple Sclerosis , slow conduction of motor and sensory pathway is due to-Loss of myelin.
41) Swelling examination: mobility in only one direction – HP showing Verocay : schwannoma
42) White foul smelling discharge in genitalia with itching. o/e strawberry vagina: Trichomonas vaginalis
43) Mucin and breast lesion - colloid carcinoma
44) Hard lump on upper outer quadrant of breast-FIBROADENOMA
45) Swan neck deformity +PIP involved DIP spared- Rheumatoid Arthritis
46) Knee joint bone tumor,30 year with giant cells – Giant Cell Tumor (GCT)
47) Absence of dystrophin-DMD
48) Suprasellar calcification: Craniopharyngioma
49) Patient has fatigue and not gaining weight. Body is warm. Investigation will show-Low TSH and high T3/T4
50) Hurthle cells and lymphocytic infiltrates – Hashimoto
51) Thyroid swelling with Orphan annie eye Histopath – Papillary Thyroid carcinoma
52) A child develops septic shock following meningitis. On examination the child has a petechial rash as shown in the image :-MENINGOCOCCUS
53) Female with ambiguous genitalia-21 alpha hydroxylase deficiency
54) Not seen in ACTH deficiency-HYPERPIGMENTATION
55) Most common endocrine pancreatic neoplasm-INSULINOMA
56) Most common site of Gastrinoma in MEN1-DUODENUM
57) Which of the following is the cause of donovanosis: Klebsiella granulomatosis
58) An HIV positive patient with a CD4 count of 300/cumm presents with mucosal lesions in the mouth as shown in the figure. On microscopy budding yeasts and pseudo-hyphae are seen. What is the likely diagnosis: CANDIDASIS
59) Malaria Fever Image : P falciparum
60) Elderly patient presenting with increasing in size of mole over face which was pre-existing present, diagnosis is: Lentigo Maligna