A 67-year-old woman has experienced severe nausea, vomiting, early satiety, and a 9-kg weight loss over the past 4 months. On physical examination, she has mild muscle wasting. Upper gastrointestinal endoscopy shows that the entire gastric mucosa is eroded and has an erythematous, cobblestone appearance. Upper gastrointestinal radiographs show that the stomach is small and shrunken. Which of the following is most likely to be found on histologic examination of a gastric biopsy specimen?
□ (A) Early gastric carcinoma
□ (B) Gastrointestinal stromal tumor
□ © Granulomatous inflammation
□ (D) Chronic atrophic gastritis
□ (E) Signet-ring cell adenocarcinoma