Which genetic condition is most common in Caucasians?

Which genetic condition is most common in Caucasians?

1.Sickle cell anaemia
2.Alpha 1 antitrypsin deficiency
3.Haemophilia A
4.Hereditory spherocytosis
5.Cystic fibrosis

Ans:
Cystic fibrosis

explanation:

Cystic fibrosis is an autosomal recessive condition caused by a mutation in the CFTR gene which produces an anion channel that is important in the creation of sweat, digestive fluids and mucous. The most common specific mutation is delta F508 which is found in 1 in 30 Caucasians. Heterozygous carriers are thought to have a survival advantage by being more resistant to dehydration from diarrhoea.