What is one key difference between the two lesions?

A female patient presents with a few week history of a growth on her eyes (see image). This is the second time the lesion has occurred in the past year. She states that the lesion feels warm and is tender to touch. She has no other relevant medical history and is on no medications. The ophthalmology resident insists that the lesion is a hordeolum, but the attending feels that this is a chalazion. What is one key difference between the two lesions?

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A. Hordeolum has been linked to elevated levels of cholesterol but not chalazion

B. Chalazion is due to blockage of the meibomian glands, whereas hordeolum is due to blockage of the Zeis glands

C. On palpation, chalazion is not tender, whereas hordeolum is painful

D. Hordeolum represent collection of neutrophils but chalazion contain multinucleated giant cells