Triad of skin lesions, asymmetric mononeuritis multiplex and eosinophilia are seen in?
A. Cryoglobulinemic vasculitis
B. Polyarteritis nodosa
C. Churg Strauss Syndrome
D. Giant cell arteritis
Correct answer : C. Churg Strauss Syndrome
Churg Strauss Syndrome
Churg Strauss Syndrome is a small vessel vasculitis.
Biopsy of affected site reveals small vessel vasculitis with eosinophilic infiltration of vessel wall.
Cryoglobulinemic vasculitis
Cryoglobulinemic vasculitis presents with rash over lower limbs, arthralgia, Raynaud’s phenomenon and neuropathy
Polyarteritis nodosa
Polyarteritis nodosa presents with fever, myalgia, arthralgia, multisystem involvement and palpable purpura.
Giant cell arteritis
Cardinal symptom of giant cell arteritis is headache localised to temporal or occipital region.
Visual disturbances can occur.
Catastrophic presentation is with blindness in one eye.
It is commonly associated with polymyalgia rheumatica.
Ref: Davidson’s Principles and Practice of Medicine, 22nd ed, p1117-1119