A 60-year-old man presents with the skin lesion pictured in Figure. Which of the following is the most likely diagnosis?
- erythema nodosum
- acanthosis nigricans
- herpes zoster
- alopecia variegata
- bullous pemphigoid
View Explanation
Bullous pemphigoid is most common in older adults. It is not as severe as pemphigus vulgaris, and histology reveals an absence of acantholysis, and immunofluorescence reveals specific antibodies in the basement membrane area.