Q 42. A woman with infertility receives an ovary transplant from her sister who
is an identical twin. What type of graft it is?
A. Xenograft
B. Autograft
C. Allograft
D. Isograft.
Ans. D
Q 43. Virus mediated transfer of host DNA from one cell to another is known as:
A. Transduction.
B. Transformation.
C. Transcription.
D. Integration.
Ans. A
Q 44. In the small intestine, cholera toxin acts by:
A. ADP-ribosylation of the G regulatory protein.
B. Inhibition of adenyl cyclase.
C. Activation of GTPase.
D. Active absorption of NaCl
Ans. A
Q 45. HIV can be detected and confirmed by:
A. Polymerase chain reaction (PCR)
B. Reverse transcriptase - PCR
C. Real time PCR
D. Mimic PCR.
Ans. B
Q 46. With reference to infections with Escherichia coli the following are true
except:
A. Enteroaggregative E. coli is associated with pwesistent diarrhoea.
B. Enterohemorrhagic E.coli can cause haemolytic uraemic syndrome.
C. Enteroinvasive E. coli produces a disease similar to salmonellosis.
D. Enterotoxigenic E.coli is a common cause of travelers diarrhoea.
Ans. C
Q 47. The following statements are true regarding melioidosis except:
A. It is caused by Burkholderia mallei.
B. The agent is a grain negative aerobic bacteria.
C. Bipolar staining of the aetiological agent is seen with methylene blue stain.
D. The most common form of melioidosis is pulmonary infection.
Ans. A
Q 48. The following bacteria are most often associated with acute neonatal
meningitis except:
A. Escherichia coli.
B. Streptococcus agalactiae.
C. Neisseria meningitidis.
D. Listeria monocytogenes.
Ans. C
Q 49. All of the following Vibrio sp. are halophilic, except:
A. V. cholerae.
B. V. parahaemolyticus.
C. V. alginolyticus.
D. V. fluvialis.
Ans. A
Q 50. All of the following organisms are known to survive intracellularly
except:
A. Neisseria meningitides.
B. Salmonella typhi.
C. Streptococcus pyogenes.
D. Legionella pneumophila.
Ans. C
Q 51. The capsule of Cryptococus neoformans in a CSF sample is best seen by:
A. Grams stain.
B. India ink preparation.
C. Giemsa stain.
D. Methanamine-silver stain.
Ans. B
Q 52. Viruses can be isolated from clinical samples by cultivation in the
following except:
A. Tissue culture.
B. Embryonated eggs.
C. Animals.
D. Chemicaly defined media.
Ans. D
Q 53. It is true regarding the normal microbial flora present on the skin and
mucous membranes that:
A. It cannot be eradicated by antimicrobial agents.
B. It is absent in the stomach due to the acidic pH.
C. It establishes in the body only after the neonatal period.
D. The flora in the small bronchi is similar to that of the trachea.
Ans. A
Q 54. An army jawan posted in a remote forest area had fever and headache. His
fever was 104°F and pulse was 70 per mibn. He had an erythematous lesion of
about 1 cm on the leg surrounded by small vesicles, along with generalized
lymphadenopathy at the time of presentation to the referral hospital. His blood
sample was collected to perform serology for the diagnosis of Rickettsial
disease. Which one of the following results in Weil-Felix reaction will be
diagnostic in this clinical setting:
A. High OX-2.
B. High OX-19.
C. High OX-K.
D. High OX-19 and OX-2.
Ans. C
Q 55. Adenosine deaminase (enzyme) deficiency is associated with:
A. Severe combined immunodeficiency (SCID)
B. X-linked agammaglobulinemia.
C. Transient hypogammaglobulinemia of infancy.
D. Chronic granulomatous disease.
Ans. A
Q 56. Which of the following viral infections is transmitted by tick?
A. Japanese encephalitis.
B. Dengue fever.
C. Kyasanur forest disease (KFD).
D. Yellow fever.
Ans. C
Q 57. Atypical pneumonia can be caused by the following microbial agents except:
A. Mycoplasma pneumoniae.
B. Legionella pneumophila.
C. Human Corona virus.
D. Klebsiella pneumoniae.
Ans. D
Q 58. The serum concentration of which of the following human IgG subclass is
maximum?
A. IgG1.
B. IgG2.
C. IgG3.
D. IgG4.
Ans. A
Q 59. Chlamydia trachomatis is associated with the following except:
A. Endemic trachoma.
B. Inclusion conjunctivitis.
C. Lymphogranuloma venereum.
D. Community acquired pneumonia.
Ans. D
Q 60. The following statements are true regarding Clostridium perfringens
except:
A. It is commonest cause of gas gangrene.
B. It is normally present in human faeces.
C. The principal toxin of C.perfringens is the alpha toxin.
D. Gas gangrene producing strains of C.perfringens produce heat resistant
spores.
Ans. D
Q 61. The most common organism amongst the following that causes acute
meningitis in an AIDS patients is:
A. Streptococcus pneumoniae.
B. Streptococcus agalactiae.
C. Cryptococcus neoformans.
D. Listeria monocytogenes.
Ans. C
Q 62. A bacterial disease that has been associated with the 3 “Rs” i.e., rats,
ricefields, and rainfall is:
A. Leptospirosis.
B. Plague.
C. Melioidosis.
D. Rodent-bite fever.
Ans. A
Q 63. A child was diagnosed to be suffering from diarrhoea due to Campylobacter
jejuni. Which of the following will be the correct environmental conditions of
incubation of the culture plates of the stool sample:
A. Temperature of 42°C and microaerophilic.
B. Temperature of 42°C and 10% carbon dioxide.
C. Temperature of 37°C and microaerophilic.
D. Temperature of 37°C and 10% carbon dioxide.
Ans. A
Q 64. Which one of the following statements is true regarding Chlamydia
pneumoniae:
A. Fifteen serovars have been identified as human pathogens.
B. Mode of transmission is by the airborne bird excreta.
C. The cytoplasmic inclusions present in the sputum specimen are rich in
glycogen.
D. The group specific antigen is responsible for the production of complement
fixing antibodies.
Ans. D
Q 65. Type I hypersensitivity is mediated by which of the following
immunoglobulins?
A. IgA.
B. IgG.
C. IgM.
D. IgE.
Ans. D