In which one of the following is the HLA-B27 antigen least likely to be present?
- Men with ankylosing spondylitis
2) Young women with pauciarticular juvenile rheumatoid arthritis (JRA)
- Men with reactive arthritis
- Men with psoriatic arthritis
Young women with early-onset pauciarticular disease commonly have antinuclear antibodies. The rheumatoid factor is not present in this group. Patients with late-onset pauciarticular disease are predominantly men and have a high incidence of HLA-B27–associated iridocyclitis. The rheumatoid factor–positive polyarticular disease and the rheumatoid factor–negative polyarticular disease are rarely, if ever, associated with uveitis.