The HLA-B27 antigen least likely to be present?

NEET PG Ophthalmology
#1

In which one of the following is the HLA-B27 antigen least likely to be present?

  1. Men with ankylosing spondylitis
    2) Young women with pauciarticular juvenile rheumatoid arthritis (JRA)
  2. Men with reactive arthritis
  3. Men with psoriatic arthritis

explanation

Young women with early-onset pauciarticular disease commonly have antinuclear antibodies. The rheumatoid factor is not present in this group. Patients with late-onset pauciarticular disease are predominantly men and have a high incidence of HLA-B27–associated iridocyclitis. The rheumatoid factor–positive polyarticular disease and the rheumatoid factor–negative polyarticular disease are rarely, if ever, associated with uveitis.