Sylvian point corresponds to?

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November 2015questions
Sylvian point corresponds to ?
Asterion
Pterion
Glabella
Lambdoid

Inca bone related to ?
Inter parietal bone
Base of occipital bone
Behind mastoid

Liraglutide is a ?
PPAR gamma agonist
Glp 1 agonist
Dpp antagonist
Sulphonyl urea

G6PD deficiency
A) a type of AD disorder
B)does not protect against malaria
C) present as chronic haemolytic anaemia
D) common cause of neonatal jaundice

LANGENBECK triangle corresponds to?
cervical nodes separated from axillary nodes by?
sex determination best bone is?
most specific feature of drowning??

Pain reduces when lifting the testis
A) torsion testis
B) seminona
C) epididymitis
D) scrotal hernia

Alemtuzumab?
Catapult bone?
drug with max Vd?
rule of halves seen in?

Trigeminal nerve and nucleus ambigus.?
General visceral efferent
Spl visceral afferent
Somatic efferent
Spl visceral efferent

Brain tumours
1.METASTASIS
m.c tumour Lung>breast>melanoma
prostate and breast cancer—metastasis to dura mimics
meningioma,ALSO CAUSES SPINAL CORD COMPRESSION
leptomeningeal mets/meningeal carcinomatosis—hematological
malignancies**(MOST COMMON CAUSE ACUTE LEUKEMIA ) ,breast
cancer ,lung ca
2.TUBEROUS SCLEROSIS
SUBEPENDYMAL GIANT CELL ASTROCYTOMA
TSC1 gene—chromosome 9 (hamartin)
TSC2 gene—chromosome 16 (tuberin)
3.NF-1
chromosome 17(neurofibromin)
optic nerve gliomas,astrocytoma,meningioma
4.NF-2
chromosome 22(merlin /moesin ,ezrin ,radixin like protein )
B/L vestibular schwannomas ,MULTIPLE MENINGIOMA,spinal
ependymomas ,astrocytoma
5.COLLOID CYSTS
Third ventricle
headache,obstructive hydrocephalus
6.DERMOID CYSTS
midline location
posterior fossa
Rx:Surgery
7.EPIDERMOID CYSTS
CP angle ,suprasellar
Rx:surgery
8.DYSEMBRYOBLASTIC NEUROEPITHELIAL TUMOURS
Temporal lobes
refractory seizures
Rx:surgery
9.CRANIOPHARYNGIOMA
suprasellar
mixed solid-Cystic lesion
Bimodal distribution
Rx:surgery +RT
10.PITUITARY TUMOURS
Microadenomas (<1cm),functioning secretes hormones
macroadenomas (>1cm),non functioning,MASS EFFECTS
11.MENINGIOMA
women more affected
NF-2
H/O cranial irradiation
arise from dura mater
composed of meningothelial *arachnoid cap cells
location :cerebral convexities
partially calcified
DURAL TAIL
12.PINEAL REGION TUMOURS
parinaud syndrome (impaired upgaze and accomodation)
13.MEDULLOBLASTOMA
M.C malignant brain tumour in children
arises from granule cell progenitors
posterior fossa
Gorlin syndrome —patched 1 mutations —sonic hedgehog
pathway
Turcot syndrome
Homer wright rosettes
seeding into CSF
14.EPENDYMOMAS
arises from ependymal cells
4th ventricle,posterior cranial fossa(m.csite)
adult—spinal cord,filum terminale–myxopapillary
15.OLIGODENDROGLIOMAS
fried egg appearance
1p and 19q deletion—sensitive to chemotherapy
16.ASTROCYTOMA
GRADE 1:PILOCYTIC ASTROCYTOMA
M.C tumour in children
cerebellum
cystic lesion WITH ENHANCING MURAL NODULE
SEGA associated with tuberous sclerosis–mTOR inhibitors are used
GRADE 2 ASTROCYTOMA
Seizure in young adults
Temozolomide
GRADE 3 :ANAPLASTIC ASTROCYTOMA
high grade
4-5 decade
GRADE 4:GLIOBLASTOMA MULTIFORME
M.C cause of malignant primary bone tumours
6-7 decade
ring enhancing mass with central necrosis and surrounding edema
Tumour with O methyl guanine DNA methyl transferase —
resistant to TEMOZOLOMIDE
bevacizumab

  1. Councilman bodies - hepatitis, yellow fever
  2. Gamma gandy bodies - congestive splenomegaly
  3. Negri bodies - rabies
  4. Lewy bodies - Parkinson’s disease
  5. Hirano bodies - Alzheimer’s disease
  6. Ferruginous bodies - asbestosis
  7. Asteroid bodies - sarcoidosis, sporotrichosis
  8. Schaumann bodies - sarcoidosis
  9. Verrocay bodies - schwannoma
  10. Call exner bodies - granulosa cell
  11. Schiller duval bodies - endodemal sinus Tumor
  12. Ascoff bodies - rheumatic fever
  13. Civatte body - lichen planus
  14. Creola bodies - bronchial asthma
  15. Donovan bodies - lymphogranuloma venerum
  16. Henderson Peterson bodies - molluscum contagiosum
  17. Michaelis guttmann body - malakoplakia
  18. Pick bodies - pick disease
  19. Zebra bodies - metachromatic leucodystrophy
  20. Barr body - inactivated X chromosome

PENTALOGY OF CANTRELL:
1.Ectopia cordis
2.midline supra umbilical abdominal defect
3.deficiency of anterior diaphragm
4.deficiency of lower sternum
5.intra cardiac defect ( VSD / TOF / LEFT VENTRICLE
diverticulum)
GARROD’S TETRAD
1.AL binism
2.C ystinuria
3.A Lkaptonuria
4.p entosuria
mnemonic:ALCAPA