Severe muscle weakness is seen in?
A. Cori disease
B. Andersen disease
C. McArdle disease
D. Tarui disease
Correct answer : B. Andersen disease
Glycogen storage disease – liver biopsy
Andersen disease is a type 4 glycogen storage disease.
It occurs due to deficiency of brancher enzyme.
It usually presents in infancy with severe muscle weakness.
Cirrhosis can also occur.
Ref: Davidson’s Principles and Practice of Medicine, 22nd edition, p450
Image credits: Nephron. Licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license. File:Glycogen storage disease in liver - very high mag.jpg - Wikimedia Commons
