Renal failure pathology (309/1700)

A pt presents with complete anuria following prolonged hypotension and shock in a pt who bled
profusely from a placental abruption. What is the most probable dx?

a. Post viral infection
b. Acute papillary necrosis
c. Acute cortical necrosis
d. HUS
e. Renal vein thrombosis

answer: C

Renal cortical necrosis is a rare cause of acute renal failure secondary to ischemic necrosis of the renal cortex. The lesions are usually caused by significantly diminished renal arterial perfusion secondary to vascular spasm, microvascular injury, or intravascular coagulation. Renal cortical necrosis is usually extensive, although focal and localized forms occur. In most cases, the medulla,

Pregnancy-related risk factors
Pregnancy-related conditions (more than 50% of cases) that may lead to renal cortical necrosis include the following:

Placental abruption
Infected abortion
Prolonged intrauterine fetal death
Severe eclampsia

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