Lipoatrophy can occur in patients treated with?
A. Abacavir
B. Tenofovir
C. Stavudine
D. Maraviroc
Correct answer : C. Stavudine
The use of thymidine analogue NRTI stavudine is associated with lipoatrophy.
When lipoatrophy occurs, therapy should be switched to non thymidine NRTI like abacavir or tenofovir.
This will result in gradual resolution of lipoatrophy.
Ref: Davidson’s Principles and Practice of Medicine, 22nd edition, p409