Leukocytoclastic vasculitis secondary to antibiotics

A 45 year-old gentleman who was to the hospital five weeks with acute bacterial endocarditis. After an appropriate antibiotic regimen was started and he became stable, he was transferred to six-week course of IV antibiotics. On week 5, the patient developed a rash on his lower extremities which were palpable hemorrhagic papules coalescing into plaques, bilateral and symmetric on lower extremities. The most likely diagnosis is :-

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  1. Leukocytoclastic vasculitis secondary to antibiotics
  2. Septic emboli with hemorrhage
  3. Urticarial vasculitis
  4. DIC secondary to sepsis

View Explanation

Most likely cause of skin findings.

Leukcytoclastic vasculitis secondary to antibiotics

Septic emboli with hemorrhage : these lesions tend to occur on the distal extremities

Urticarial vasculitis : presents with a different morphology, which is more nodular and less diffuse

DIC secondary to sepsis : in DIC, coagulation studies are abnormal