GASTRIC PROTECTANTS (Medications)

The client with a gastric ulcer has a prescription for sucralfate (Carafate), 1 g by mouth 4 times daily. The nurse schedules the medication for which times?

1. With meals and at bedtime
2. Every 6 hours around the clock
3. One hour after meals and at bedtime
4. One hour before meals and at bedtime

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GASTRIC PROTECTANTS (Medications)

Misoprostol (Cytotec)
An antisecretory medication that enhances mucosal defenses
Suppresses secretion of gastric acid and maintains submucosal blood flowby promoting vasodilation
Used to prevent gastric ulcers caused by nonsteroidal anti-inflammatory drugs and aspirin.
Administered with meals
Causes diarrhea and abdominal pain
Contraindicated for use in pregnancy
Sucralfate (Carafate)
Creates a protective barrier against acid and pepsin.
Administered orally; should be taken on an empty stomach
May cause constipation
May impede absorption of warfarin sodium (Coumadin), phenytoin (Dilantin), theophylline, digoxin (Lanoxin), and some antibiotics; should be administered at least 2 hours apart from these medications.