ESSENTIALS OF ORTHOPAEDICS AND PMR
1 C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma, whose levels rise in response to inflammation.
2 It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells.
3 Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via the C1Q complex
4 CRP is synthesized by the liver in response to factors released by macrophages and fat cells (adipocytes)
5 It is a member of the pentraxin family of proteins.
6 It is not related to C-peptide (insulin) or protein C (blood coagulation).
7 C-reactive protein was the first pattern recognition receptor (PRR) to be identified ( vv imp )
ESSENTIALS OF PMR - FUNCTIONAL IMPROVEMENT AND QUALITY OF LIFE
ADL’s training and occupational therapy role in polio treatment
A ) Washing and toilet: supporting rails, bath or shower seats and adjustments to the height of washing bowl, basin or bath may be provided
B ) Dressing: clothes with zip fasteners and Velcro may be provided
C ) Housing, domestic aids and furniture may be modified for the severely disabledTransport:
D ) wheelchairs must be strong enough for rough roads and be patient propelled whenever possible.
E ) Motorized wheelchairs and cars with special control are also available