A 44yo man presents with periorbital and pedal edema. 24h urine shows 8g of protein/d and
serum cholesterol=7mmol/L. Renal biopsy results are awaited. What would be the most likely dx?
a. Minimal change disease
b. Glomerulonephropathy
c. Membranous glomerulonephropathy
d. FSGS
e. IgA nephropathy
f. Mesangiocapillary
answer: C
Nephrotic syndrome: PALE
Proteinuria > marked
Albumin low
Lipids high
Edema
causes: in order of most proteinuria
• Minimal change GN …commonest cause in children
• Membranous GN…commonest cause of in adults
• FSGS