All the following drugs do not cause bronchoconstriction except?
a. Atenolol
b. Salbutamol
c. Salmetrol
d. Ipratropium bromide
e. Cocaine
answer A
non selective B blockers b1/b2 theorectically can cause bronchospasm as they are the opposite of B2 agonists which cause bronchodilation, however cardio selective B1 blockers have a negligible effect on b2 receptors, so they won’t cause bronchospasm
Clinical Uses
Class/Drug HTN Angina Arrhy MI CHF Comments
Non-selective β1/β2
carteolol X ISA; long acting; also used for glaucoma
carvedilol X X α-blocking activity
labetalol X X ISA; α-blocking activity
nadolol X X X X long acting
penbutolol X X ISA
pindolol X X ISA; MSA
propranolol X X X X MSA; prototypical beta-blocker
sotalol X several other significant mechanisms
timolol X X X X primarily used for glaucoma
β1-selective
acebutolol X X X ISA
atenolol X X X X
betaxolol X X X MSA
bisoprolol X X X X
esmolol X X ultra short acting; intra or postoperative HTN
metoprolol X X X X X MSA
nebivolol X relatively selective in most patients; vasodilating (NO release)