Dinitrophenol causes:
A. Inhibition of ATP synthase
B. Inhibition of electron transport
C. Uncoupling of oxidation and phosphorylation
D. Accumulation of ATP
Correct answer : C. Uncoupling of oxidation and phosphorylation
Dinitrophenol uncouples oxidation and phosphorylation in the respiratory chain. The hydrogen ions re enter the mitochondrial matrix without ATP synthesis. The energy is released as heat.