Biochemistry: AIIMS MAY 2003 Q6

  1. Replication and transcription are similar processes in mechanistic terms because both
    a) Use RNA primers for initiation
    b) Use deoxy-ribo-nucleotides as precursors
    c) Are semi conserved events
    d) Involve phosphodiester bond formation with elongation occurring in the 5′-> 3′ direction

Explanation:
Replication and transcription: Similarities
The general steps of initiation, elongation and termination with 5′-> 3′ polarity with formation of phosphodiester bond
Large multi-component initiation complex
Adherence of Watson Crick base pairing rule
Answer: Involve phosphodiester bond formation with elongation occurring in the 5′-> 3′ direction
Ref: Harper 30th Ed. Page-