Biochemistry: AIIMS MAY 2003 Q13

Q-118. NADPH is produced by:
a) Glycolysis
b) Citric acid cycle
c) HMP Shunt
d) Glycogenesis

Answer: HMP Shunt
Explanation:
HMP Shunt provides a major portion of the body’s NADPH which functions as a biochemical reductant.
Uses of NADPH:
Reductive biosynthesis- Synthesis of steroids and fatty acids
Reduction of hydrogen per-oxide
Cytochrome P450 mono-oxygenase system
Phagocytosis by WBCs
Synthesis of nitric oxide