True about drug induced SLE is –
a) CNS manifestation are common
b) Renal involvement is common
c) Antihistone antibodies are found in many
d) All with antibodies progress to lupus
e) Sex ratio is nearly equal
explanation
Drug induced lupus ervthematosus
A lupus like syndrome may develop in patients receiving a variety of drugs.
Procainamide and hydralazine are most common offenders.
Most patients do not have symptoms of lupus erythematosus.
Anti ds DNA antibody is rare
There is an extremely high frequency of antihistone antibodies.
Although multiple organs may be affected renal and CNS involvement, usually does not occur.
Sex ratio is equal (in contrast to idiopathic SLE where females are affected more commonly).