An 9-year-old boy is brought to the emergency department because of progressive lethargy

An 9-year-old boy is brought to the emergency department because of progressive lethargy, confusion, and vomiting during the past 3 days. One week ago, he developed a fever and a pruritic rash over his trunk and extremities. A photograph of the lesions is shown. His mother reports that she gave him medication to treat the fever but does not recall the specific drug. His temperature is 38°C (100.4°F), pulse is 90/min, respirations are 16/min, and blood pressure is 104/72 mm Hg. Which of the following is the most appropriate next step in management?

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  1. N-acetylcysteine
  2. Activated charcoal
  3. Antibiotics
  4. Intravenous immune globulin
  5. Supportive care