A 59 year old man with severe myxomatous mitral regurgitation is asymptomatic, with a left ventricular ejection fraction of 45% and an end-systolic diameter index of 2.9 cm/m2. The most appropriate treatment is:
A. Mitral valve repair or replacement
B. No treatment
C. ACE inhibitor therapy
D. Digoxin and diuretic therapy
Correct answer : A. Mitral valve repair or replacement
Surgical treatment of severe mitral regurgitation is recommended even if the person is asymptomatic when the LV ejection fraction drops below 60% and there is progressive LV dysfunction.
All of the following may cause ST segment elevation on EKG, except:
A. Early repolarization variant
B. Constrictive pericarditis
C. Ventricular aneurysm
D. Prinzmetal angina
Correct answer : B. Constrictive pericarditis
ST elevation can occur in acute pericarditis.
Palpable purpura could occur in the following conditions, except:
A. Thrombocytopenia
B. Small-vessel vasculitis
C. Gonococcal infection
D. Acute meningococcemia
Correct answer : A. Thrombocytopenia
Palpable purpura does not occur in thrombocytopenia.
Causes of palpable purpura
Rocky mountain spotted fever
Acute meningococcemia
Disseminated gonococcal infection
Ecthyma gangrenosum
Henoch Schonlein purpura
Polyarteritis nodosa
Leucocytoclastic vasculitis
All of the following are the causes of relative polycythemia except:
A. Dehydration
B. Dengue haemorrhagic fever
C. Gaisbock syndrome
D. High altitude
Correct answer : D. High altitude
People living at high altitudes have absolute polycythemia due to increased erythropoietin synthesis.
In which of the following conditions Splenectomy is not useful?
A. Herediatary spherocytosis
B. Porphyria
C. Thalassemia
D. Sickle cell disease with large spleen
Correct answer : B. Porphyria
Splenectomy has little role in the management of porphyria
Renal artery stenosis may occur in all of the following except:
A. Atherosclerosis
B. Fibromuscular dysplasia
C. Takayasu’s arteritis
D. Polyarteritis nodosa
Correct answer : D. Polyarteritis nodosa
Causes of renal artery stenosis:
Atherosclerosis
Giant cell arteritis
Fibromuscular dysplasia
Takayasu arteritis
Tranplant renal artery stenosis
Antiphospholipid antibody syndrome
The presence of anti Saccharomyces cerevisae antibody is a surrogate marker of one of the following:
A. Celiac disease
B. Crohn’s disease
C. Ulcerative colitis
D. Tropical sprue
Correct answer : B. Crohn’s disease
Saccharomyces cerevisae antibody positivity:
Chron’s disease – 60-70%
Ulcerative colitis – 10-15%
Anticentromere antibodies are most commonly associated with:
A. Diffuse cutaneous systemic sclerosis
B. Mixed connective tissue disease
C. CREST syndrome
D. Polymyositis
Correct answer : C. CREST syndrome
Anticentromere antibodies are seen mostly in those with CREST syndrome. (40-80% patients with CREST syndrome are anticentromere antibody positive)
You are here: Home » AIPGMEE » AIPGMEE 2006 » .
Medicine – MCQ 143 – Drug induced lupus antibody
Drug induced lupus can be identified by:
A. Anti histone antibodies
B. Double stranded DNA antibodies
C. Antinuclear antibodies
D. Anti SM antibodies
Correct answer : A. Anti histone antibodies
Anti histone antibodies are present in more than 95% individuals with drug induced lupus.