AIIMS PG Entrance May 2015 – MCQ 22 – Recurrent respiratory papillomatosis

Topical therapy for recurrent respiratory papillomatosis is?
A. Zinc
B. Ranitidine
C. Acyclovir
D. Cidofovir

Correct answer : D. Cidofovir

Human-Papillomavirus-Electron-Microscopy

Human Papillomavirus Electron MicroscopyHuman Papillomavirus Electron Micrograph

Recurrent respiratory papillomatosis (also known as laryngeal papillomatosis) is a disease caused by Human Papillomavirus (HPV).
It is characterised by warty growths in the upper respiratory tract which can cause significant airway obstruction.
 Patients present with hoarseness of voice and breathing difficulty.
Treatment is by removal of the tumour via surgery / carbon dioxide laser.
It may be supplemented by intralesional injection of cidofovir in moderate to severe disease.
Interferon therapy can also be used.