Adult growth hormone deficiency (GHD) is confirmed by which of the following?
A low IGF binding protein-3 (IGFBP3) concentration
A low IGF-1 concentration
A peak growth hormone (GH) concentration of 6 mU/L (2 µg/L) with insulin-induced
hypoglycaemia This is the correct answer
An undetectable random growth hormone concentration. Incorrect answer selected
Suppression of GH below 2 mU/l (1.3 µg/L) with an oral glucose tolerance test
The diagnosis of adult GHD depends on a peak GH response of less than 9 mU/L to insulin-induced
hypoglycaemia.