A 58-year-old man comes to the emergency department because of coughing,

A 58-year-old man comes to the emergency department because of coughing, fatigue, and significant trouble breathing for the past few days. He lives in the southwestern United States and has had issues with mice in his home. One week ago, he was cleaning out the large amounts of dust in his attic and ended up inhaling some of it. His temperature is 39.4°C (103.0°F), pulse is 88/min, respirations are 24/min, and blood pressure is 96/68 mm Hg. Physical examination shows wheezing bilaterally on auscultation of the chest. Laboratory viral studies show an enveloped, single-stranded, negative-sense, circular RNA with three segments. Chest x-ray shows pulmonary edema and further evidence of pneumonia. Over the next few hours, his respiratory status declines further. He requires intubation and mechanical ventilation. Which of the following is the most likely cause of this condition?

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  1. Hantavirus
  2. Norovirus
  3. Rhabdovirus
  4. Rotavirus
  5. West Nile virus