6.Which of these disease can be treated by enzyme replacement?

Methylation of Cytidine residues of DNA will cause(AIIMS 2014 May)
a) No Change
b) Decrease gene expression
c) Mutation
d) Increase in gene expression
DNA Methylation
Generally decreases the gene expression or Gene silencing.
DNA Demethylation
Generally increases the gene expression .

5.Which of the following is not an intermediate of TCA Cycle? (AIIMS 2014 May)
a) Acetyl CoA
b) Citrate
c) Succinyl CoA
d) Alpha Keto Glutarate
Acetyl CoA and Oxaloacetate are the starting materials of TCA Cycle.

6.Which of these disease can be treated by enzyme replacement?
a) Gaucher’s Disease
b) Fabry’s Disease
c) Pompe’s disease
d) Sanfilippo Disease